Associations between plasma osteopontin, sex, and 2-year global and cardiorenal outcomes in older outpatients screened for CKD: a secondary analysis of the SCOPE study

pOPN levels were significantly lower in women than in men but associated with all-cause mortality in women only; increase in serum pOPN was associated with eGFR decline over time in all patients, but with stronger associations among women. Assessment of pOPN may help identifying older female participants at risk of poor outcomes.

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Publication Details

Journal
Clinical Kidney Journal
Published
2024-11-19
DOI
https://doi.org/10.1093/ckj/sfae336
Citations
1
Primary Topic
Bone and Dental Protein Studies
Type
article
Field-Weighted Citation Impact
0.47

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article

Associations between plasma osteopontin, sex, and 2-year global and cardiorenal outcomes in older outpatients screened for CKD: a secondary analysis of the SCOPE study

Rada Artzi‐Medvedik, Anna Rita Bonfigli, Luca Soraci, Ilan Yehoshua et al.
1 citations
Clinical Kidney Journal
Bone and Dental Protein Studies
0.47
article

Associations between plasma osteopontin, sex, and 2-year global and cardiorenal outcomes in older outpatients screened for CKD: a secondary analysis of the SCOPE study

Rada Artzi‐Medvedik, Anna Rita Bonfigli, Luca Soraci, Ilan Yehoshua, Łukasz Kroc, Federica Lenci, Tomasz Kostka, Małgorzata Pigłowska, Cornel Sieber, Rafael Moreno‐González, Mirko Di Rosa, Fabrizia Lattanzio, Revekka Kaltsa, Ellen Freiberger, Silvia Bustacchini, Roberta Galeazzi, Françesc Formiga, Mónica González Alonso, Cinzia Giammarchi, Itshak Melzer, Sonja Lindner, Sabrina Garasto, Sabine Britting, Susanne Muck, Romano Firmani, Christian Weingart, Katarzyna Smyj, Xavier Corbella, Pamela Carrillo García, Jeannette Goudzwaard, Robertina Giacconi, A. Mark Clarfield, Robert Kob, Silvia Bolognini, Johan Ärnlöv, Josep M. Cruzado, Paola D’Ascoli, Elizaveta Fife, Lara Guardado Fuentes, Lucia Muglia, Bartłomiej K. Sołtysik, Moreno Nacciariti, Joanna Kostka, Harmke A. Polinder‐Bos, Demetrio Postacchini, Stephan Theobaldy, Gerhard Wirnsberger, Axel Carl Carlsson, Carolina Polo, Andreas Bekmann, Tobias Feldreich, Sara Laínez Martínez, Francesco Mattace‐Raso, Carolin Herzog, Agnieszka Guligowska, Serena Marcozzi, Giuseppina Di Stefano, Kinga Zel, Fernando Tornero Molina, Regina Roller‐Wirnsberger, Gijsbertus Ziere, Raffaella Moresi, Enrico Bordoni, Lisanne Tap, Stefano Della Bella, Paolo Fabbietti, María Mombiedro Pérez, Andrea Corsonello, Natalia Sosowska, Mauro Provinciali, Anna Antoszczyk, Anders Olof Larsson, José Antonio Herrero Calvo, Pedro Gil Gregório, Yurema Martínez, Alexandra Renz, Yehudit Melzer, Agnieszka Gutowska
article en
1 citations

Abstract

pOPN levels were significantly lower in women than in men but associated with all-cause mortality in women only; increase in serum pOPN was associated with eGFR decline over time in all patients, but with stronger associations among women. Assessment of pOPN may help identifying older female participants at risk of poor outcomes.

Clinical Kidney JournalVol. 17(12)
Dalarna University (SE), Uppsala University (SE), Ben-Gurion University of the Negev (IL), Friedrich-Alexander-Universität Erlangen-Nürnberg (DE), Medical University of Graz (AT), Erasmus MC (NL), Bellvitge University Hospital (ES), Karolinska Institutet (SE), Maccabi Healthcare Services (IL), Institut d'Investigació Biomédica de Bellvitge (ES), Kantonsspital Winterthur (CH), Department of Medical Sciences (RU), Institute for Biomedicine (IT), Medical University of Lodz (PL), Primary Health Care (QA), Stockholm Health Care Services (SE), Istituto Nazionale di Riposo e Cura per Anziani (IT), Erasmus University Rotterdam (NL)
European Commission
Good health and well-being
Openalex Percentile: Top 30%
Bone and Dental Protein Studies
0.47
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