Does <i>de novo</i> malignancy heighten the risk of rejection in kidney transplant recipients?

In kidney transplant recipients with <i>de novo</i> malignancies, death with a functioning graft remains significant. However, allograft loss rates do not increase compared with those without malignancies, and rejection risk is reduced, especially in older and chemotherapy-treated patients. These findings suggest that managing immunosuppression reduction in this population may be appropriate, but further research is needed to determine optimal care strategies.

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Publication Details

Journal
Clinical Kidney Journal
Published
2024-11-19
DOI
https://doi.org/10.1093/ckj/sfae349
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Does de novo malignancy heighten the risk of rejection in kidney transplant recipients?

Aslıhan Pekmezci, Nurhan Seyahi, Aydın Türkmen, Cansu Erel et al.
2 links
Clinical Kidney Journal
Renal Transplantation Outcomes and Treatments
article

Does de novo malignancy heighten the risk of rejection in kidney transplant recipients?

Aslıhan Pekmezci, Nurhan Seyahi, Aydın Türkmen, Cansu Erel, Cebrail Karaca, Sinan Trabulus, Latif Karahan, Mevlüt Tamer Dinçer, Erol Demir
article en

Abstract

In kidney transplant recipients with <i>de novo</i> malignancies, death with a functioning graft remains significant. However, allograft loss rates do not increase compared with those without malignancies, and rejection risk is reduced, especially in older and chemotherapy-treated patients. These findings suggest that managing immunosuppression reduction in this population may be appropriate, but further research is needed to determine optimal care strategies.

Clinical Kidney JournalVol. 17(12)
Koç University (TR), Istanbul University-Cerrahpaşa (TR), Istanbul University (TR)
Good health and well-being
Openalex Percentile: Top 60%
Renal Transplantation Outcomes and Treatments
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