Hyperoside induces ferroptosis in chronic myeloid leukemia cells by targeting NRF2
The present analyses indicate that hyperoside can target the NRF2/SLC7A11/GPX4 axis to induce ferroptotic CML cell death.
Authors
- Qing Chai (ORCID: https://orcid.org/0000-0001-6609-9785)
- Chunling Guo
- Jianfeng Wei (ORCID: https://orcid.org/0000-0001-9209-0063)
- Yong Qin (ORCID: https://orcid.org/0000-0003-4743-938X)
- Long Li (ORCID: https://orcid.org/0000-0002-7693-9722)
- Zhaoyang Lu (ORCID: https://orcid.org/0000-0003-3367-2674)
- Huimin Liu (ORCID: https://orcid.org/0009-0007-0175-3476)
Institutions
- Shanxi Medical University (CN)
- Sir Run Run Shaw Hospital (CN)
- Zhejiang Lab (CN)
- Second Hospital of Shanxi Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1186/s10020-024-01002-7
- Citations
- 18
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 4.21
Funders
- National Natural Science Foundation of China