The Impact of HLA-A29 Homozygosity and of the Second HLA-A Allele on Susceptibility and Severity of Birdshot Chorioretinitis
Homozygosity for HLA-A29 increased the risk of developing BSCR without affecting disease severity. The under-representation of HLA-A32 in patients with BSCR suggests a potential protective role.
Authors
- Romain Lhotte (ORCID: https://orcid.org/0000-0002-6131-5415)
- Eli A. Stahl (ORCID: https://orcid.org/0000-0002-1192-0561)
- Thierry Tabary (ORCID: https://orcid.org/0000-0001-6301-589X)
- Sahar Gelfman (ORCID: https://orcid.org/0000-0002-4727-7862)
- Antoine P. Brézin (ORCID: https://orcid.org/0000-0001-8461-3119)
- Valentin Clichet (ORCID: https://orcid.org/0000-0002-1303-4619)
- Jordan Loeliger (ORCID: https://orcid.org/0000-0001-8826-9730)
- Jean‐Luc Taupin (ORCID: https://orcid.org/0000-0002-5766-046X)
- J. Cohen (ORCID: https://orcid.org/0000-0003-4214-4419)
- Souhila Kecili
- Dominique Monnet (ORCID: https://orcid.org/0000-0001-6846-6120)
- Linda Imikirene
Institutions
- Inserm (FR)
- Regeneron (United States) (US)
- Université Paris Cité (FR)
- University Hospital of Basel (CH)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Saint-Louis (FR)
- Université de Reims Champagne-Ardenne (FR)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1167/iovs.65.13.47
- Citations
- 2
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 1.08
Funders
- Regeneron Pharmaceuticals