Virtual Gene Panels Have a Superior Diagnostic Yield for Inherited Rare Diseases Relative to Static Panels
Our findings support slice testing as an efficient and flexible platform that facilitates updates to gene lists to achieve high clinical sensitivity and utility.
Authors
- Roudha Alfalasi
- Sathishkumar Ramaswamy (ORCID: https://orcid.org/0000-0002-7467-6658)
- Ahmad Abou Tayoun (ORCID: https://orcid.org/0000-0002-9134-1673)
- Shruti Sinha (ORCID: https://orcid.org/0009-0008-5273-2920)
- Shruti Shenbagam (ORCID: https://orcid.org/0009-0000-1470-4875)
- Nour Halabi
- Maha El Naofal
- Alan Taylor (ORCID: https://orcid.org/0009-0006-7755-1355)
- Ruchi Jain (ORCID: https://orcid.org/0000-0001-9395-1275)
- Massomeh Sheikh Hassani
- Sawsan Alyafei
Institutions
- Mohammed Bin Rashid University of Medicine and Health Sciences (AE)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1093/clinchem/hvae183
- Citations
- 5
- Primary Topic
- Genomics and Rare Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.75