Metabolomic Profiling of Open-Angle Glaucoma Etiologic Endotypes: Tohoku Multi-Omics Glaucoma Study
Integrated metabolomic profiles identified five distinct etiologic endotypes of OAG, suggesting pathological mechanisms related with a high-risk group of central vision loss progression in the Japanese population.
Authors
- Yu Yokoyama (ORCID: https://orcid.org/0000-0001-5275-2923)
- Akira Narita (ORCID: https://orcid.org/0000-0002-9076-0710)
- Noriko Himori (ORCID: https://orcid.org/0000-0001-8307-0458)
- Yoshihiko Raita (ORCID: https://orcid.org/0000-0002-5805-9369)
- Kazuko Omodaka
- Toru Nakazawa (ORCID: https://orcid.org/0000-0002-5591-4155)
- Masato Akiyama (ORCID: https://orcid.org/0000-0002-1879-5476)
- S. Koshiba (ORCID: https://orcid.org/0000-0003-2001-1949)
- Naoko Takada (ORCID: https://orcid.org/0009-0002-6783-3667)
- Jin Inoue
- Akiko Hanyuda (ORCID: https://orcid.org/0000-0002-2342-9550)
- Gen Tamiya (ORCID: https://orcid.org/0000-0002-0597-415X)
- Kazuki Hashimoto (ORCID: https://orcid.org/0000-0002-8324-2202)
- Takahiro Ninomiya (ORCID: https://orcid.org/0000-0002-2214-6698)
- Yasuko Yamamoto (ORCID: https://orcid.org/0000-0001-8825-9188)
- Kota Sato (ORCID: https://orcid.org/0000-0002-0176-5545)
- Takazumi Taniguchi
- Satoru Tsuda
- Kazuno Negishi
Institutions
- Kyushu University (JP)
- Santen (Japan) (JP)
- Tohoku University (JP)
- Keio University (JP)
- Okinawa Prefectural Chubu Hospital (JP)
- Tohoku Medical Megabank Organization (JP)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1167/iovs.65.13.44
- Citations
- 3
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.62
Funders
- Glaucoma Research Foundation
- Japan Science and Technology Agency