Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

Lenticular fluorescence can be measured rapidly, accurately, and quantitatively in vivo which provides a spatially resolved, quantitative measure of lens chemistry, including damage from oxidation and glycation. Careful interpretation of fluorescence intensities and intensity ratios can provide chemical insight into lens health. Anterior segment UV fluorescence imaging can thus serve as a useful tool for screening, monitoring, and research of lens damage and cataract formation.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2024-11-20
DOI
https://doi.org/10.1167/iovs.65.13.41
Primary Topic
Connexins and lens biology
Type
article
Field-Weighted Citation Impact
0.00

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article

Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

Angela J. Verkade, Joshua M. Herzog, Volker Sick
Investigative Ophthalmology & Visual Science
Connexins and lens biology
article

Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence

Angela J. Verkade, Joshua M. Herzog, Volker Sick
article en

Abstract

Lenticular fluorescence can be measured rapidly, accurately, and quantitatively in vivo which provides a spatially resolved, quantitative measure of lens chemistry, including damage from oxidation and glycation. Careful interpretation of fluorescence intensities and intensity ratios can provide chemical insight into lens health. Anterior segment UV fluorescence imaging can thus serve as a useful tool for screening, monitoring, and research of lens damage and cataract formation.

Investigative Ophthalmology & Visual ScienceVol. 65(13)
University of Michigan (US), Michigan United (US)
University of Michigan, National Institutes of Health, Michigan Institute for Clinical and Health Research, National Center for Advancing Translational Sciences
Openalex Percentile: Top 81%
Connexins and lens biology
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Quantitative and Rapid In Vivo Imaging of Human Lenticular Fluorescence — Angela J. Verkade, Joshua M. Herzog, et al. · Investigative Ophthalmology & Visual Science (2024) | TGRS Research Map | TGRS