Pulrodemstat, a selective inhibitor of KDM1A, suppresses head and neck squamous cell carcinoma growth by triggering apoptosis
Pulrodemstat is an effective therapeutic drug for HNSCC. Thus, the TET3/KDM1A axis may account for the malignant phenotype of HNSCC.
Authors
- Xiaofeng Weng
- Yuqing Chen (ORCID: https://orcid.org/0009-0004-7166-8144)
- Junjun Yang
- Cheng Jiang
Institutions
- Jiangnan University (CN)
- Nanjing Maternity and Child Health Care Hospital (CN)
- Wuxi No.2 People's Hospital (CN)
- Wuxi Taihu Hospital (CN)
- Wuxi People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1186/s40360-024-00807-w
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Nanjing Medical University