Does Interoceptive Awareness Influence Depression Through Anxiety in Peruvian Adults? A Mediation Analysis

Interoceptive awareness is currently gaining considerable attention and is in an active phase of research, supported by a growing body of empirical evidence from diverse fields such as neurophysiology, cognitive neuroscience, mind–body therapies, psychiatry, and psychometrics. The aim of this study was to examine the relationship between interoceptive awareness, anxiety, and depression in Peruvian adults. A total of 414 participants residing in Lima, Peru, were included, with 85% being young adults aged 18–27 years (252 women = 61%; 162 men = 39%; age range = 18–64; M age = 23.4). The results indicated that the indirect effect of interoceptive awareness on depression through anxiety accounted for 61.7% of the mediation, while the direct effect of interoceptive awareness on depression accounted for 38.3%. In conclusion, the hypothesis that anxiety negatively mediates the relationship between interoceptive awareness and depression in Peruvian adults was confirmed. This research may have implications in clinical settings, particularly for the prevention and psychotherapeutic intervention of anxiety and depression, through the promotion of adaptive interoceptive awareness.