Enhancing genetic discovery through narrow phenotyping in schizophrenia

Subphenotyping schizophrenia may enhance the discovery of genetic factors affecting its development and progression. The GWAS and TWAS findings revealed general mechanisms involved in the development of schizophrenia with potentially severe outcomes, such as synapse regulation, inflammation, and apoptosis.

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Publication Details

Journal
Journal of Psychiatric Research
Published
2024-11-20
DOI
https://doi.org/10.1016/j.jpsychires.2024.11.033
Citations
3
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
1.65
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article

Enhancing genetic discovery through narrow phenotyping in schizophrenia

Andrey Shingaliev, А. В. Козлов, Kira Nebogina, S. M. Yudin et al.
3 citations
Journal of Psychiatric Research
Genetic Associations and Epidemiology
1.65
article

Enhancing genetic discovery through narrow phenotyping in schizophrenia

Andrey Shingaliev, А. В. Козлов, Kira Nebogina, S. M. Yudin, Anna Yakovchik, Maria Bruttan, Anton А. Keskinov, Olga Pavlova, Д. А. Каштанова, Еlena Zelenova, М. В. Иванов, В. В. Макаров, Aleksander Nekrasov, V. S. Yudin, Sergey A. Kraevoy, А. А. Мамчур, Lorena Matkava, Pavlov Ka, Sergey I. Mitrofanov, Mikhail Terekhov, Veronika Skvortsova, Anna Morozova, Aleksandra Nekrasova, Vasilisa A. Astafieva
article en
3 citations

Abstract

Subphenotyping schizophrenia may enhance the discovery of genetic factors affecting its development and progression. The GWAS and TWAS findings revealed general mechanisms involved in the development of schizophrenia with potentially severe outcomes, such as synapse regulation, inflammation, and apoptosis.

Journal of Psychiatric ResearchVol. 181
Federal Agency for Health and Social Development (RU), Federal Medical Research Centre for Psychiatry and Narcology (RU), Federal Medical-Biological Agency (RU)
Openalex Percentile: Top 14%
Genetic Associations and Epidemiology
1.65
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Enhancing genetic discovery through narrow phenotyping in schizophrenia — Andrey Shingaliev, А. В. Козлов, et al. · Journal of Psychiatric Research (2024) | TGRS Research Map | TGRS