Development of a Composite Score Based on Carbohydrate Antigen 19-9 Dynamics to Predict Survival in Carbohydrate Antigen 19-9–Producing Patients With Pancreatic Ductal Adenocarcinoma After Neoadjuvant Treatment
The composite score consisting of CA19-9 levels at diagnosis, after neoadjuvant treatment, and its dynamics demonstrates prognostic discrimination between low and high scores. However, better predictive biomarkers are needed to facilitate treatment decisions during neoadjuvant treatment.
Authors
- Greg D. Sacks (ORCID: https://orcid.org/0000-0003-1205-6477)
- Brian Kaplan (ORCID: https://orcid.org/0009-0005-0686-5544)
- Kelly J. Lafaro (ORCID: https://orcid.org/0000-0002-7070-7269)
- Steven M. Cohen (ORCID: https://orcid.org/0000-0002-6633-8173)
- Veronica Galimberti (ORCID: https://orcid.org/0000-0002-5781-1483)
- Ingmar F. Rompen (ORCID: https://orcid.org/0000-0002-0257-1654)
- Richard A. Burkhart (ORCID: https://orcid.org/0000-0003-1087-0870)
- Olivıer Turrini (ORCID: https://orcid.org/0000-0002-2144-2380)
- Joseph R. Habib (ORCID: https://orcid.org/0000-0003-3445-2278)
- Elisabetta Sereni
- Lucas R. Perez Rivera (ORCID: https://orcid.org/0000-0002-6582-3003)
- Jonathan Garnier (ORCID: https://orcid.org/0000-0001-5481-2926)
- Jin Peng He (ORCID: https://orcid.org/0000-0001-9149-2247)
- D. Brock Hewitt (ORCID: https://orcid.org/0000-0001-6556-3830)
- Ammar A. Javed (ORCID: https://orcid.org/0000-0002-5463-5250)
- D. Vatti
- William R. Burns (ORCID: https://orcid.org/0000-0002-3049-4377)
- Christopher L. Wolfgang
Institutions
- University of Verona (IT)
- Johns Hopkins University (US)
- Aix-Marseille Université (FR)
- Heidelberg University (DE)
- Johns Hopkins Medicine (US)
- University Hospital Heidelberg (DE)
- Institut Paoli-Calmettes (FR)
Publication Details
- Journal
- JCO Precision Oncology
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1200/po.24.00193
- Citations
- 4
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 1.13