The therapeutic effects of curcumin on polycystic ovary syndrome by upregulating PPAR-γ expression and reducing oxidative stress in a rat model
This study demonstrates that curcumin effectively restores ovarian morphology, hormone levels, and estrous cycles in PCOS rats. These effects may be linked to its ability to reduce oxidative stress in ovaries via the upregulation of PPAR-γ. Curcumin shows promise as a potential drug for the treatment of PCOS.
Authors
- Wei Zhang (ORCID: https://orcid.org/0000-0001-7463-6990)
- Lei Xu (ORCID: https://orcid.org/0000-0001-5518-0510)
- Chaolin Huang (ORCID: https://orcid.org/0000-0001-6240-7963)
- Cong Peng (ORCID: https://orcid.org/0000-0001-9475-3684)
- Yutai Zhao
- Ling Lu
Institutions
- First Affiliated Hospital of Chengdu Medical College (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-11-20
- DOI
- https://doi.org/10.3389/fendo.2024.1494852
- Citations
- 15
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 8.06
Funders
- Chengdu Medical College