Exploring the pathogenesis, biomarkers, and potential drugs for type 2 diabetes mellitus and acute pancreatitis through a comprehensive bioinformatic analysis
This study suggests that abnormal lipid metabolism is a potential crosstalk mechanism between T2DM and AP. In addition, we established a two-gene model for the clinical diagnosis of T2DM and AP and identified imatinib as a potential therapeutic agent for both diseases.
Authors
- Xi Yang
- Yunshu Zhang
- J. Li (ORCID: https://orcid.org/0000-0001-5676-0330)
- Xingchi Jiang (ORCID: https://orcid.org/0000-0002-6953-644X)
- Yu‐Xuan Shang
- S. Liu (ORCID: https://orcid.org/0000-0001-8618-9956)
- Yang Yao (ORCID: https://orcid.org/0000-0002-7975-3405)
- Jifeng Liu (ORCID: https://orcid.org/0000-0002-2874-2706)
- Lei Zhong (ORCID: https://orcid.org/0000-0002-2974-6231)
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-11-20
- DOI
- https://doi.org/10.3389/fendo.2024.1405726
- Citations
- 6
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.44