Optimization of initial dosage of quetiapine in schizophrenic patients: effects of fluvoxamine or duloxetine coadministration
The present study was a pilot effort at investigating the potential DDIs and optimal initial dosage of quetiapine in schizophrenic patients based on PPK. The initial dosages of quetiapine administered to the patients were optimized according to the coadministration of fluvoxamine or duloxetine.
Authors
- Su‐Mei He
- Di Yin
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-9797-8384)
- Dongdong Wang (ORCID: https://orcid.org/0000-0002-4019-5530)
- Chenxu Liu (ORCID: https://orcid.org/0000-0001-5561-2010)
- Cun Zhang (ORCID: https://orcid.org/0000-0002-9381-9730)
- Yue Zhang (ORCID: https://orcid.org/0000-0002-8463-0223)
- Yanjun Jin
Institutions
- Xuzhou Medical College (CN)
- Nanjing Maternity and Child Health Care Hospital (CN)
- Suzhou Municipal Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-11-20
- DOI
- https://doi.org/10.3389/fphar.2024.1496043
- Citations
- 3
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Jiangsu Commission of Health
- Government of Jiangsu Province
- Xuzhou Medical University