Skeletal muscle is independently associated with grade 3–4 toxicity in advanced stage pancreatic ductal adenocarcinoma patients receiving chemotherapy
Sarcopenia and early muscle and fat wasting during FOLFIRINOX treatment were associated with treatment-related toxicity, warranting exploration of body composition guided personalized dosing of chemotherapeutics to limit DLTs.
Authors
- Leonard Wee (ORCID: https://orcid.org/0000-0003-1612-9055)
- Gilles Wenmaekers
- David van Dijk (ORCID: https://orcid.org/0000-0003-3911-9925)
- Mariëlle M.E. Coolsen (ORCID: https://orcid.org/0000-0002-1608-6668)
- Judith de Vos‐Geelen (ORCID: https://orcid.org/0000-0003-2578-1766)
- Leroy Volmer (ORCID: https://orcid.org/0009-0001-4978-4024)
- Steven W.M. Olde Damink (ORCID: https://orcid.org/0000-0002-5202-9345)
- Ronald M. van Dam (ORCID: https://orcid.org/0000-0001-8415-5090)
- Merel R. Aberle (ORCID: https://orcid.org/0000-0003-1990-1784)
- Sander S. Rensen (ORCID: https://orcid.org/0000-0001-5054-8400)
- Ralph Brecheisen (ORCID: https://orcid.org/0000-0001-9937-2602)
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
- Maastro Clinic (NL)
Publication Details
- Journal
- Clinical Nutrition ESPEN
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1016/j.clnesp.2024.11.004
- Citations
- 1
- Primary Topic
- Cancer survivorship and care
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- NUTRIM School of Nutrition and Translational Research in Metabolism