Abnormal choroid plexus, hippocampus, and lateral ventricles volumes as markers of treatment‐resistant major depressive disorder
These findings corroborate the link between TRD and neuroinflammation, as ChP volume could be considered a putative marker of central immune activity. The lack of significant differences in all of the region of interest volumes between patients with TSD and HCs may highlight the specificity of these features to TRD, possibly providing new insights into the specific neurobiological underpinnings of this condition.
Authors
- Raffaella Zanardi (ORCID: https://orcid.org/0000-0001-5941-5663)
- Melania Maccario
- Cristina Colombo (ORCID: https://orcid.org/0000-0001-7310-7341)
- Francesco Benedetti (ORCID: https://orcid.org/0000-0003-4949-856X)
- Elisa Melloni (ORCID: https://orcid.org/0000-0002-6742-8373)
- B. Bravi (ORCID: https://orcid.org/0000-0003-2568-4181)
- Chiara Milano (ORCID: https://orcid.org/0000-0003-2128-3751)
- Marco Paolini (ORCID: https://orcid.org/0000-0001-5731-5925)
- Laura Raffaelli (ORCID: https://orcid.org/0009-0007-3295-0907)
Institutions
- Vita-Salute San Raffaele University (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- Psychiatry and Clinical Neurosciences
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1111/pcn.13764
- Citations
- 3
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Fondazione Cariplo
- Ministero della Salute