Transcatheter intervention of modified Blalock–Taussig shunts in patients with hypoplastic left heart syndrome undergoing stage 1 palliation

The transcatheter intervention of the MBTSs in patients with HLHS undergoing NP is considered both safe and potentially life-saving in emergent situations. This approach may facilitate improved pulmonary development, postpone the need for subsequent surgeries, and provide medium-term palliative care for critically ill patients. However, managing late complications such as stent thrombosis remains a significant challenge. Our findings indicate that risk factors for shunt thrombosis include using ECMO therapy, underlying coagulation disorders, impaired lymphatic drainage, requiring multiple stents within the shunt, and a prior history of thrombosis before intervention. Dual antiplatelet therapy is recommended to alleviate the risk of thrombotic events in this population.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2024-11-20
DOI
https://doi.org/10.3389/fcvm.2024.1502801
Primary Topic
Congenital Heart Disease Studies
Type
article
Field-Weighted Citation Impact
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article

Transcatheter intervention of modified Blalock–Taussig shunts in patients with hypoplastic left heart syndrome undergoing stage 1 palliation

Katja Schneider, Nathalie Mini, Marian Mikus
Frontiers in Cardiovascular Medicine
Congenital Heart Disease Studies
article

Transcatheter intervention of modified Blalock–Taussig shunts in patients with hypoplastic left heart syndrome undergoing stage 1 palliation

Katja Schneider, Nathalie Mini, Marian Mikus
article en

Abstract

The transcatheter intervention of the MBTSs in patients with HLHS undergoing NP is considered both safe and potentially life-saving in emergent situations. This approach may facilitate improved pulmonary development, postpone the need for subsequent surgeries, and provide medium-term palliative care for critically ill patients. However, managing late complications such as stent thrombosis remains a significant challenge. Our findings indicate that risk factors for shunt thrombosis include using ECMO therapy, underlying coagulation disorders, impaired lymphatic drainage, requiring multiple stents within the shunt, and a prior history of thrombosis before intervention. Dual antiplatelet therapy is recommended to alleviate the risk of thrombotic events in this population.

Frontiers in Cardiovascular MedicineVol. 11
University Hospital Bonn (DE), Deutsches Herzzentrum München (DE)
Openalex Percentile: Top 68%
Congenital Heart Disease Studies
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