The 7-Methylguanosine (m7G) methylation METTL1 acts as a potential biomarker of clear cell renal cell carcinoma progression
METTL1 associated with m7G may serve as a potential biomarker for ccRCC prognosis and diagnosis. Moreover, it may affect the prognosis of ccRCC by regulating the tumor immune microenvironment, providing a potential therapeutic target for immunotherapy. These results provide a new perspective on the role of M7G-related RNAs in ccRCC pathogenesis.
Authors
- Yudong Hu
- Yifan Zhan (ORCID: https://orcid.org/0000-0001-6974-0486)
- Zhengze Shen (ORCID: https://orcid.org/0000-0002-2752-896X)
- Yi Liu (ORCID: https://orcid.org/0000-0002-4998-5547)
- Jiao Liu (ORCID: https://orcid.org/0009-0005-3286-8861)
- Bin Tang (ORCID: https://orcid.org/0000-0001-8986-040X)
- Ling Zhong (ORCID: https://orcid.org/0000-0002-1549-0423)
- Jing Guo
- Yuan Yu (ORCID: https://orcid.org/0000-0003-1009-5464)
Institutions
- Dalian Medical University (CN)
- Second Affiliated Hospital of Chongqing Medical University (CN)
- Chongqing Cancer Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1016/j.tranon.2024.102202
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.47