The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors
By binding to NR4A, AEA elicits an anti-inflammatory response in vascular smooth muscle cells. NR4A-binding by AEA analogues may represent novel anti-inflammatory agents.
Authors
- Beatrice Pflüger‐Müller
- Andreas Zimmer (ORCID: https://orcid.org/0000-0001-6618-6264)
- Ewgenij Proschak (ORCID: https://orcid.org/0000-0003-1961-1859)
- Stefan Knapp (ORCID: https://orcid.org/0000-0001-5995-6494)
- Paola Munoz‐Tello (ORCID: https://orcid.org/0000-0002-5225-1907)
- Virna Margarita Martín Giménez (ORCID: https://orcid.org/0000-0003-2188-977X)
- Jan Heering (ORCID: https://orcid.org/0000-0002-4922-1993)
- Tom Teichmann (ORCID: https://orcid.org/0009-0009-5402-3834)
- Dominique Thomas (ORCID: https://orcid.org/0000-0002-1053-129X)
- Andreas Weigert (ORCID: https://orcid.org/0000-0002-7529-1952)
- Irmgard Tegeder (ORCID: https://orcid.org/0000-0001-7524-8025)
- Douglas J. Kojetin (ORCID: https://orcid.org/0000-0001-8058-6168)
- Timothy Warwick (ORCID: https://orcid.org/0000-0002-6804-2931)
- Maike Windbergs (ORCID: https://orcid.org/0000-0001-9475-699X)
- Walter Manucha (ORCID: https://orcid.org/0000-0002-2279-7626)
- Simonida Zehr (ORCID: https://orcid.org/0009-0005-8510-657X)
- Dagmar Meyer zu Heringdorf (ORCID: https://orcid.org/0000-0003-1246-9677)
- Matthias S. Leisegang (ORCID: https://orcid.org/0000-0002-6084-6484)
- Stefan Günther (ORCID: https://orcid.org/0000-0002-5594-4549)
- Felix E. B. Brettner (ORCID: https://orcid.org/0000-0002-7356-3897)
- Gerd Geißlinger (ORCID: https://orcid.org/0000-0003-0552-7488)
- Ralf P. Brandes (ORCID: https://orcid.org/0000-0002-8035-0048)
- Robert Gurke (ORCID: https://orcid.org/0000-0001-8218-1295)
- Iris‐S. Bibli
- Fiona Sailer
- Henrik Dirks
Institutions
- Goethe University Frankfurt (DE)
- University of Bonn (DE)
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Universidad Nacional de Cuyo (AR)
- Vanderbilt University (US)
- Max Planck Institute for Heart and Lung Research (DE)
- Fraunhofer Institute for Translational Medicine and Pharmacology (DE)
- Universidad Católica de Cuyo (AR)
- German Centre for Cardiovascular Research (DE)
- University Hospital Frankfurt (DE)
- Instituto de Medicina y Biología Experimental de Cuyo (AR)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1111/bph.17366
- Citations
- 9
- Primary Topic
- Nuclear Receptors and Signaling
- Type
- article
- Field-Weighted Citation Impact
- 2.41
Funders
- Deutscher Akademischer Austauschdienst
- Deutsche Forschungsgemeinschaft
- Dr. Rolf M. Schwiete Stiftung
- National Institutes of Health
- Agencia Nacional de Promoción Científica y Tecnológica