The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors

By binding to NR4A, AEA elicits an anti-inflammatory response in vascular smooth muscle cells. NR4A-binding by AEA analogues may represent novel anti-inflammatory agents.

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Publication Details

Journal
British Journal of Pharmacology
Published
2024-11-19
DOI
https://doi.org/10.1111/bph.17366
Citations
9
Primary Topic
Nuclear Receptors and Signaling
Type
article
Field-Weighted Citation Impact
2.41

Funders

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article

The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors

Beatrice Pflüger‐Müller, Andreas Zimmer, Ewgenij Proschak, Stefan Knapp et al.
9 citations
British Journal of Pharmacology
Nuclear Receptors and Signaling
2.41
article

The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors

Beatrice Pflüger‐Müller, Andreas Zimmer, Ewgenij Proschak, Stefan Knapp, Paola Munoz‐Tello, Virna Margarita Martín Giménez, Jan Heering, Tom Teichmann, Dominique Thomas, Andreas Weigert, Irmgard Tegeder, Douglas J. Kojetin, Timothy Warwick, Maike Windbergs, Walter Manucha, Simonida Zehr, Dagmar Meyer zu Heringdorf, Matthias S. Leisegang, Stefan Günther, Felix E. B. Brettner, Gerd Geißlinger, Ralf P. Brandes, Robert Gurke, Iris‐S. Bibli, Fiona Sailer, Henrik Dirks
article en
9 citations

Abstract

By binding to NR4A, AEA elicits an anti-inflammatory response in vascular smooth muscle cells. NR4A-binding by AEA analogues may represent novel anti-inflammatory agents.

British Journal of PharmacologyVol. 182(5)
Goethe University Frankfurt (DE), University of Bonn (DE), Consejo Nacional de Investigaciones Científicas y Técnicas (AR), Universidad Nacional de Cuyo (AR), Vanderbilt University (US), Max Planck Institute for Heart and Lung Research (DE), Fraunhofer Institute for Translational Medicine and Pharmacology (DE), Universidad Católica de Cuyo (AR), German Centre for Cardiovascular Research (DE), University Hospital Frankfurt (DE), Instituto de Medicina y Biología Experimental de Cuyo (AR)
Deutscher Akademischer Austauschdienst, Deutsche Forschungsgemeinschaft, Dr. Rolf M. Schwiete Stiftung, National Institutes of Health, Agencia Nacional de Promoción Científica y Tecnológica
Good health and well-being
Openalex Percentile: Top 11%
Nuclear Receptors and Signaling
2.41
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