POEM in Achalasia Type III and Non-Achalasia Esophageal Motility Disorders

Abstract Background POEM has gained popularity in the treatment of achalasia and other esophageal motility disorders worldwide and most of reports have demonstrated the remarkable efficiency of POEM as a treatment of achalasia. This study will demonstrate efficiency of POEM as a treatment of achalasia type 3 and other non-achalasia esophageal disorders. Type III achalasia represents about 10% of all cases of achalasia with most of cases presenting near age 60. It presents with similar clinical profile to other types of achalasia and spastic EMD; in which chest pain occur mainly during swallowing, with more severe dysphagia and regurgitation, and thus, more weight loss. Aim of the Work To demonstrate efficiency of POEM as a treatment of achalasia type 3 and other non-achalasia esophageal disorders. Patients and Methods This was a pilot prospective observational study and patients will be selected from endoscopy centers in Egypt. Results Our study showed that statistically significant decrease in mean Eckardt score was present in patients who underwent POEM indicating resolution of symptoms of esophageal motility disorder. Also, adverse outcomes were present, indicating high safety of POEM as a therapeutic procedure. Conclusion POEM is safe and effective in the management of achalasia type III as well as other non-achalasia EMD. However, more research is needed to generalize the utilization of this procedure to help more patients.