Impact of treosulfan exposure on clinical outcome after allogeneic stem cell transplantation in children: A substudy of 2 phase 2 trials

These findings suggest that treosulfan exposure after standardized body surface area-based dosing is appropriate in paediatric allo-HSCT.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2024-11-19
DOI
https://doi.org/10.1111/bcp.16339
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
0.00

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article

Impact of treosulfan exposure on clinical outcome after allogeneic stem cell transplantation in children: A substudy of 2 phase 2 trials

Rita Beier, Krzysztof Kałwak, Katarzyna Drabko, Ansgar Schulz et al.
7 links
British Journal of Clinical Pharmacology
Hematopoietic Stem Cell Transplantation
article

Impact of treosulfan exposure on clinical outcome after allogeneic stem cell transplantation in children: A substudy of 2 phase 2 trials

Rita Beier, Krzysztof Kałwak, Katarzyna Drabko, Ansgar Schulz, Bernd Gruhn, Franco Locatelli, Monika Mielcarek‐Siedziuk, Peter Bader, Jolanta Goździk, Joachim Baumgart, Birgit Burkhardt, Petr Sedláček, Ajay Vora, Johann Greil, Dirk Reinhardt, Selim Corbacioglu, Xieran Li, Jan Styczyński, Paul‐Gerhardt Schlegel, Katharine Patrick, Jochen Kehne
article en

Abstract

These findings suggest that treosulfan exposure after standardized body surface area-based dosing is appropriate in paediatric allo-HSCT.

British Journal of Clinical PharmacologyVol. 91(3)
Goethe University Frankfurt (DE), Medical University of Lublin (PL), Jagiellonian University (PL), Heidelberg University (DE), Great Ormond Street Hospital (GB), University Hospital Heidelberg (DE), Nicolaus Copernicus University (PL), Medizinische Hochschule Hannover (DE), Wroclaw Medical University (PL), University Hospital in Motol (CZ), University Hospital Münster (DE), Essen University Hospital (DE), Sheffield Children's NHS Foundation Trust (GB), Bambino Gesù Children's Hospital (IT), Universitätsklinikum Würzburg (DE), Jena University Hospital (DE), University Hospital Ulm (DE), Medac (Germany) (DE), University College London (GB), University of Regensburg (DE)
Amgen, Medac
Openalex Percentile: Top 66%
Hematopoietic Stem Cell Transplantation
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