Nonalcoholic Fatty Liver Disease among Diabetic Patients on Oral Hypoglycemic versus Insulin

Abstract Background Non-alcoholic fatty liver disease (NAFLD) is a group of clinicopathologic diseases defined by lipid buildup in the liver parenchyma in people with no history of heavy alcohol consumption. Steatosis alone appears to be benign within this spectrum, but non-alcoholic steatohepatitis (NASH), marked by ballooning degeneration and sinusoidal/pericellular fibrosis, can be progressive. Aim of the Work to detect the prevalence of non-alcoholic fatty liver disease among diabetic patients on oral hypoglycemic versus insulin. Patients and Methods this cross-sectional study was conducted in Internal medicine Department, Ain Shams hospitals in 6 months from April till October 2022 on Diabetic Patients on Oral Hypoglycemic or Insulin. All patients were divided into two groups: Group A: Diabetic patients on Oral Hypoglycemic drugs. Group B: Diabetic patients on Insulin. Results There was no statistically significant difference between the studied groups as regard baseline data (Age, sex, BMI and hypertension). There was statistically significant difference between the studied groups as regard fast blood glucose and non-significant difference as regard HBA1C. There was no statistically significant difference between the studied groups as regard CRP. Conclusion the prevalence of non-alcoholic fatty liver disease (NAFLD) in diabetic patients on hypoglycemic group was less than in patient taking insulin