Effectiveness of U/S Guided Erector Spinea Plane Block for Post-Operative Pain Control in Breast Surgeries

Abstract Background Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer-related mortality among females in more than 100 countries. The traditional therapeutic approaches for breast cancer include surgery, radiation therapy, chemotherapy, Immunotherapy and endocrine therapy, surgical resection is still considered to be the primary and most effective therapy. Objective To evaluate the analgesic effect of ultrasound-guided erector spinae plane (ESP) block in breast surgery postoperatively Methods This was randomized controlled clinical trial that was held in major operating theaters in el demerdash hospital, Ain Shams University, Cairo, Egypt for 6 months on females undergoing breast surgeries aged between 21 - 45 years. Results Our results reported that there was highly statistically significant difference found between Group I and Group II regarding Postoperative pain scores Immediately, Postoperative pain scores After 5min, Postoperative pain scores After 10 min, and there was no highly statistically significant difference found between Group I and Group II regarding Postoperative pain scores After 15min, Postoperative pain scores After 20min, Postoperative pain scores After 25min and Postoperative pain scores After 30min. There was highly statistically significant difference found between Group I and Group II regarding Total morphine consumption (mg) and Number of patients requiring morphine. Also, there was highly statistically significant difference found between Group I and Group II regarding Mean arterial blood pressure (mmHg) Immediately, and there was no highly statistically significant difference found between Group I and Group II regarding Mean arterial blood pressure (mmHg) After 5min, Mean arterial blood pressure (mmHg) After 10 min, Mean arterial blood pressure (mmHg) After 15 min, Mean arterial blood pressure (mmHg) After 20 min, Mean arterial blood pressure (mmHg) After 25 min and Mean arterial blood pressure (mmHg) After 30 min. Regarding Patients satisfaction, there was statistically significant difference found between Group I and Group II Conclusion Ultrasound-guided ESP block with general an aesthesia offers superior post-operativeanalgesia compared to general an aesthesia alone in patients undergoing unilateral non-reconstructive breast cancer surgeries and is associated with better patient satisfaction scores at discharge. There was no significant difference in intraoperative morphine consumption. The ultrasound-guided ESP block appears to be an effective block for postoperative analgesia in breast cancer surgery.