Evaluation of Albumin-Bilirubin Score in Predicting Post-Transplant Complications Following Adult Living Donor Liver Transplantation

Abstract Background Liver transplantation is a life-saving therapeutic intervention that contributes to a better quality of life in patients with end-stage or acute liver failure. Receiving a lobe of liver from living donor is a life time gift don’t waste it and be grateful. Patients and Methods Our study was conducted on patients underwent LT at Liver Transplantation Unit, Cairo Fatemic Hospital (Cairo, Egypt) from April 2018 till December 2021 with follow up of enrolled patient for 6 months' afterword. There were 112 patients underwent LT at the period of the study, 108 of them met the inclusion criteria and were enrolled in the study while 4 cases were excluded (pediatric cases). The study protocol conformed to the ethical guidelines of the 1975 Declaration of Helsinki, and was approved by Ain Shams University Research Ethics Committee (REC). Results This study showed male predominance among enrolled patients 71 cases (65.7%), with mean age of 48.09 ± 12.79 years' old and mean BMI of 27.84 ± 5.99. The most commonly recorded indications of LT in our study were HCC, ESLD due to HCV or HBV, AIH and cryptogenic liver cirrhosis. The overall incidence of post-operative complications was 43.5% (47 out of 108 cases) and the most frequent cause was biliary complications. ALBI score was higher in complicated cases than uncomplicated cases without reaching statistical significance. Conclusion The study concluded that ALBI score may be a good prognostic score for prediction of post- transplant complications following living donor liver transplantation to be evaluated in larger scale studies.