FUT8 upregulates CD36 and its core fucosylation to accelerate pericyte-myofibroblast transition through the mitochondrial-dependent apoptosis pathway during AKI-CKD
These results further identify FUT8 and CD36 as potential targets for the treatment in the progression of AKI-CKD.
Authors
- Qingzhu Tang
- Yuanyuan Shang (ORCID: https://orcid.org/0000-0003-2349-3648)
- Xiangning Du
- Hongli Lin (ORCID: https://orcid.org/0000-0003-3403-7584)
- Weidong Wang (ORCID: https://orcid.org/0000-0003-2523-3145)
- Xu Zhang (ORCID: https://orcid.org/0000-0002-0608-6509)
- Fan Yang (ORCID: https://orcid.org/0000-0003-2583-8603)
- Ziran Wang (ORCID: https://orcid.org/0000-0001-8163-044X)
- Jiaojiao Hao
- Xianan Guo
Institutions
- Dalian Medical University (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1186/s10020-024-00994-6
- Citations
- 6
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 2.04
Funders
- National Natural Science Foundation of China
- Dalian Medical University