Formulation and Evaluation of Valproic Acid Microemulsions for Enhanced Transfollicular Delivery in Guinea Pig Skin
The ME formulations significantly enhanced VPA penetration into both epidermal and follicular pathways compared with aqueous solution. The composition of the MEs, particularly the oil content, water content, and surfactant/cosurfactant ratio, played a crucial role in determining the physicochemical properties and skin permeation parameters of VPA.
Authors
- Sirous Jafarian (ORCID: https://orcid.org/0000-0002-4281-5326)
- Saeed Mohammad Soleymani (ORCID: https://orcid.org/0000-0003-1462-3930)
- Anayatollah Salimi (ORCID: https://orcid.org/0000-0003-1505-7969)
- A. Salimi
Institutions
- Ahvaz Jundishapur University of Medical Sciences (IR)
- Imam Hossein Hospital (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1111/jocd.16685
- Citations
- 1
- Primary Topic
- Hair Growth and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.54
Funders
- Ahvaz Jundishapur University of Medical Sciences
- Vice Chancellor for Research and Technology, Kerman University of Medical Sciences