Association of high-density lipoprotein profile with cardiovascular risk factorsin metabolic syndrome patients

Cardiovascular disease is the number one cause of death in Indonesia. The increased risk of cardiovascular disease in obese patients is largely due to dyslipidemia. One of the important lipid profiles to observe is high-density lipoprotein (HDL). One form of early prevention that can be done is to predict the risk of cardiovascular disease in the future. The research wanted to determine the relationship of HDL profile with cardiovascular risk factors in patients with metabolic syndrome. The research design was cross-sectional. The research location used in this study was around the Surabaya area starting in March-June 2022. The research location was carried out in Rungkut District, Surabaya, Indonesia. The variables of this study were the risk of cardiovascular disease and HDL levels. Samples of patients at Siti Khodijah Throughout Hospital who met the criteria, among others: age 18- 60 years and willing to follow all research procedures. The sampling technique used was purposive sampling. Subjects who met the criteria were then asked to fill out an informed consent. Subjects assessed the risk of cardiovascular disease with the Framingham Risk Score (FRS). Test the relationship between the risk of cardiovascular disease with HDL levels with Rank Spearman. The number of respondents involved in the study was 37 people. Most of the respondents have low HDL scores and high cardiovascular risk (12 people). The value of the Spearman correlation coefficient was 0.897, indicating that there was a relationship between the HDL profile and cardiovascular risk of 89.7%. The relationship between HDL profile with cardiovascular risk was strong, HDL values were associated with cardiovascular risk. Therefore, a patient with metabolic syndrome should pay more attention to the HDL value to prevent cardiovascular-related comorbidities.