Incidence of pneumococcal disease in children in Germany, 2014–2019: a retrospective cohort study
From 2014 to 2019 there were no discernible trends in the IRs of PP or IPD, but the IRs of ACP declined in children aged < 16 years. The highest IRs of ACP, PP and IPD were observed in children < 2 years of age, highlighting the importance of infant pneumococcal vaccination in the prevention of pediatric PD. The clinical burden of pediatric PD in Germany persists. Continued surveillance of changing pneumococcal burden, serotype distribution, antimicrobial resistance and vaccination status is critical to better understand the factors driving incidence of PD and to inform future vaccination strategies.
Authors
- Timo Boellinger
- Salini Mohanty (ORCID: https://orcid.org/0000-0001-7610-6467)
- Jessica Weaver (ORCID: https://orcid.org/0000-0002-9861-3328)
- Tianyan Hu (ORCID: https://orcid.org/0009-0004-2660-8871)
- Nawab Qizilbash (ORCID: https://orcid.org/0000-0001-6950-2322)
- Wolfgang Galetzka
- Rosemarie Barnett (ORCID: https://orcid.org/0000-0002-2215-4970)
- Meghan White (ORCID: https://orcid.org/0000-0002-1215-116X)
- Bélène Podmore (ORCID: https://orcid.org/0000-0001-6627-0378)
- Dominik Obermüller
- Thomas Weiß (ORCID: https://orcid.org/0000-0003-4384-6228)
- Dennis Haeckl
Institutions
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- London School of Hygiene & Tropical Medicine (GB)
- Institute for Applied Economic Research (DE)
- MSD (Germany) (DE)
- MRC Epidemiology Unit (GB)
- University of Bath (GB)
Publication Details
- Journal
- BMC Pediatrics
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1186/s12887-024-05003-7
- Citations
- 5
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 1.93