Laryngeal Mucosal Tumor Mapping with Narrow Band Imaging and Confocal Laser Endomicroscopy
Confocal laser endomicroscopy (CLE) represents an emerging probe-based intraoperative optical imaging modality, contingent on differential fluoroscein uptake, equipped to improve intraoperative identification of subclinical mucosal disease. In the analysis herein, we describe improved sensitivity, compared to narrow band imaging and small-volume tissue biopsies, of CLE in the discrimination of occult disease based on cellular and subcellular morphology during endoscopic resection of early-staged larynx cancers. Laryngoscope, 135:1767-1770, 2025.
Authors
- C. KOCH
- Bharat Panuganti
- Amanda Atkins
- Harishanker Jeyarajan (ORCID: https://orcid.org/0000-0001-7277-2024)
- Sherin James (ORCID: https://orcid.org/0000-0002-1036-5842)
- Jason M. Warram (ORCID: https://orcid.org/0000-0001-5230-0011)
- Matti Sievert (ORCID: https://orcid.org/0000-0003-0741-4049)
- Miguel Goncalves (ORCID: https://orcid.org/0000-0002-0036-4598)
- Akhilesh Wodeyar
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- University of Alabama at Birmingham (US)
- Universitätsklinikum Erlangen (DE)
- Universitätsklinikum Würzburg (DE)
Publication Details
- Journal
- The Laryngoscope
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1002/lary.31918
- Citations
- 1
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- National Cancer Institute