Baseline triglyceride-glucose, body mass index, end-diastolic internal diameter of the left atria and creatinine are independent predictors for pulmonary hypertension in coronary artery disease patients after percutaneous coronary intervention treatm

<b>Aim:</b> To identify the predictive role of triglyceride-glucose (TyG) index in pulmonary hypertension (PH) in coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI) treatment.<b>Methods:</b> Blood biomarkers have been measured at the cross-section of entrance. The baseline and followed-up echocardiography have been performed at both cross-sections.<b>Results:</b> The incidence of PH was 8.91%. The baseline myoglobin (MYO), was significantly higher among PH patients (<i>p</i> < 0.001). In the univariate regression, body mass index (BMI <i>p</i> = 0.020), left atria end-diastolic internal diameter (LAD, <i>p</i> = 0.083), creatinine (Cr, <i>p</i> = 0.005), triglyceride (TG, <i>p</i> < 0.001), high-density lipoprotein cholesterol (HDL-C, <i>p</i> = 0.056) and TyG index (<i>p</i> = 0.002) were potential predictors for PH. Finally, the adjusted COX regression indicated that BMI (<i>p</i> = 0.001), LAD (<i>p</i> = 0.030), Cr(<i>p</i> = 0.005) and TyG index (<i>p</i> = 0.002) were independent predictors of the onset of PH.<b>Conclusion:</b> Baseline TyG index, BMI, LAD, Cr level were independent predictors for PH in CAD patients after PCI treatment.

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Journal
Biomarkers in Medicine
Published
2024-11-20
DOI
https://doi.org/10.1080/17520363.2024.2422807
Primary Topic
Pulmonary Hypertension Research and Treatments
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article
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article

Baseline triglyceride-glucose, body mass index, end-diastolic internal diameter of the left atria and creatinine are independent predictors for pulmonary hypertension in coronary artery disease patients after percutaneous coronary intervention treatm

Shizhu Bian, Litong Ran, Shilin Fu, Dehui Qian et al.
Biomarkers in Medicine
Pulmonary Hypertension Research and Treatments
article

Baseline triglyceride-glucose, body mass index, end-diastolic internal diameter of the left atria and creatinine are independent predictors for pulmonary hypertension in coronary artery disease patients after percutaneous coronary intervention treatm

Shizhu Bian, Litong Ran, Shilin Fu, Dehui Qian, Yuzheng Xu, Li Xie, Jianfei Chen, Jing Luo, Rongsheng Rao
article en

Abstract

<b>Aim:</b> To identify the predictive role of triglyceride-glucose (TyG) index in pulmonary hypertension (PH) in coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI) treatment.<b>Methods:</b> Blood biomarkers have been measured at the cross-section of entrance. The baseline and followed-up echocardiography have been performed at both cross-sections.<b>Results:</b> The incidence of PH was 8.91%. The baseline myoglobin (MYO), was significantly higher among PH patients (<i>p</i> < 0.001). In the univariate regression, body mass index (BMI <i>p</i> = 0.020), left atria end-diastolic internal diameter (LAD, <i>p</i> = 0.083), creatinine (Cr, <i>p</i> = 0.005), triglyceride (TG, <i>p</i> < 0.001), high-density lipoprotein cholesterol (HDL-C, <i>p</i> = 0.056) and TyG index (<i>p</i> = 0.002) were potential predictors for PH. Finally, the adjusted COX regression indicated that BMI (<i>p</i> = 0.001), LAD (<i>p</i> = 0.030), Cr(<i>p</i> = 0.005) and TyG index (<i>p</i> = 0.002) were independent predictors of the onset of PH.<b>Conclusion:</b> Baseline TyG index, BMI, LAD, Cr level were independent predictors for PH in CAD patients after PCI treatment.

Biomarkers in MedicineVol. 18(23)
Army Medical University (CN), Xinqiao Hospital (CN)
Good health and well-being
Openalex Percentile: Top 61%
Pulmonary Hypertension Research and Treatments
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Baseline triglyceride-glucose, body mass index, end-diastolic internal diameter of the left atria and creatinine are independent predictors for pulmonary hypertension in coronary artery disease patients after percutaneous coronary intervention treatm — Shizhu Bian, Litong Ran, et al. · Biomarkers in Medicine (2024) | TGRS Research Map | TGRS