Baseline triglyceride-glucose, body mass index, end-diastolic internal diameter of the left atria and creatinine are independent predictors for pulmonary hypertension in coronary artery disease patients after percutaneous coronary intervention treatm
<b>Aim:</b> To identify the predictive role of triglyceride-glucose (TyG) index in pulmonary hypertension (PH) in coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI) treatment.<b>Methods:</b> Blood biomarkers have been measured at the cross-section of entrance. The baseline and followed-up echocardiography have been performed at both cross-sections.<b>Results:</b> The incidence of PH was 8.91%. The baseline myoglobin (MYO), was significantly higher among PH patients (<i>p</i> < 0.001). In the univariate regression, body mass index (BMI <i>p</i> = 0.020), left atria end-diastolic internal diameter (LAD, <i>p</i> = 0.083), creatinine (Cr, <i>p</i> = 0.005), triglyceride (TG, <i>p</i> < 0.001), high-density lipoprotein cholesterol (HDL-C, <i>p</i> = 0.056) and TyG index (<i>p</i> = 0.002) were potential predictors for PH. Finally, the adjusted COX regression indicated that BMI (<i>p</i> = 0.001), LAD (<i>p</i> = 0.030), Cr(<i>p</i> = 0.005) and TyG index (<i>p</i> = 0.002) were independent predictors of the onset of PH.<b>Conclusion:</b> Baseline TyG index, BMI, LAD, Cr level were independent predictors for PH in CAD patients after PCI treatment.
Authors
- Shizhu Bian (ORCID: https://orcid.org/0000-0002-0541-0581)
- Litong Ran
- Shilin Fu
- Dehui Qian
- Yuzheng Xu (ORCID: https://orcid.org/0000-0002-9715-9565)
- Li Xie
- Jianfei Chen (ORCID: https://orcid.org/0000-0002-6786-9283)
- Jing Luo (ORCID: https://orcid.org/0000-0002-0512-5641)
- Rongsheng Rao
Institutions
- Army Medical University (CN)
- Xinqiao Hospital (CN)
Publication Details
- Journal
- Biomarkers in Medicine
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1080/17520363.2024.2422807
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00