Evaluation Of Serum Magnesium Level In Critically Ill Patient And Predict Their Clinical Outcome A Prospective Observational Study

Background: Magnesium is a crucial electrolyte involved in various physiological processes, and its deficiency is associated with poor outcomes in critically ill patients.This study aims to evaluate the relationship between serum magnesium levels and clinical outcomes, including the need for ventilator support, length of stay in the intensive care unit (ICU), and mortality risk.Methods: This single-center, prospective observational study was conducted over six months in the ICU of Vivekanandha Medical Care Hospital.A total of 66 patients aged over 18, excluding those with renal impairment, postoperative status, magnesium supplementation, or poisoning, were included.Serum magnesium levels were measured, and the APACHE IV scoring system was utilized to assess severity and predict mortality.Data were analyzed using SPSS Version 22, with a significance level set at p < 0.05. Results:The average age of participants was 69.12 13.59 years, with a majority having normal serum magnesium levels (1.90 0.48 mg/dL).Clinical parameters indicated severe illness, with a mean APACHE IV score of 103.62 48.31.Despite these findings, serum magnesium levels did not significantly correlate with ventilator support duration, mortality rates, or length of ICU stay.Statistical analyses revealed no significant impact of serum magnesium on these outcomes (p > 0.05). Conclusion:The study demonstrates that while serum magnesium plays a role in critical physiological functions, it did not significantly influence clinical outcomes in this cohort of critically ill patients.These findings highlight the complexity of magnesium's role in critical care settings and underscore the need for further research to explore its implications more comprehensively.

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Publication Details

Journal
African Journal of Biomedical Research
Published
2024-11-20
DOI
https://doi.org/10.53555/ajbr.v27i3.3595
Primary Topic
Magnesium in Health and Disease
Type
article
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article

Evaluation Of Serum Magnesium Level In Critically Ill Patient And Predict Their Clinical Outcome A Prospective Observational Study

Jayaprakash Kuppusamy
African Journal of Biomedical Research
Magnesium in Health and Disease
article

Evaluation Of Serum Magnesium Level In Critically Ill Patient And Predict Their Clinical Outcome A Prospective Observational Study

Jayaprakash Kuppusamy
article en

Abstract

Background: Magnesium is a crucial electrolyte involved in various physiological processes, and its deficiency is associated with poor outcomes in critically ill patients.This study aims to evaluate the relationship between serum magnesium levels and clinical outcomes, including the need for ventilator support, length of stay in the intensive care unit (ICU), and mortality risk.Methods: This single-center, prospective observational study was conducted over six months in the ICU of Vivekanandha Medical Care Hospital.A total of 66 patients aged over 18, excluding those with renal impairment, postoperative status, magnesium supplementation, or poisoning, were included.Serum magnesium levels were measured, and the APACHE IV scoring system was utilized to assess severity and predict mortality.Data were analyzed using SPSS Version 22, with a significance level set at p < 0.05. Results:The average age of participants was 69.12 13.59 years, with a majority having normal serum magnesium levels (1.90 0.48 mg/dL).Clinical parameters indicated severe illness, with a mean APACHE IV score of 103.62 48.31.Despite these findings, serum magnesium levels did not significantly correlate with ventilator support duration, mortality rates, or length of ICU stay.Statistical analyses revealed no significant impact of serum magnesium on these outcomes (p > 0.05). Conclusion:The study demonstrates that while serum magnesium plays a role in critical physiological functions, it did not significantly influence clinical outcomes in this cohort of critically ill patients.These findings highlight the complexity of magnesium's role in critical care settings and underscore the need for further research to explore its implications more comprehensively.

African Journal of Biomedical Research
Openalex Percentile: Top 75%
Magnesium in Health and Disease
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