In vitro detection of cancer cells using a novel fluorescent choline derivative
The results showed that CFA preferentially accumulated in cancer cells rather than in normal cells. These findings suggest that CFA may be a potential diagnostic probe for discriminating healthy tissues from malignant tissues due to its specific and highly sensitive features; CFA may also represent a useful tool for in vitro/ex vivo investigations of choline metabolism in patients with cervical and breast cancers.
Authors
- Anna E. Caprifico (ORCID: https://orcid.org/0000-0002-2170-1063)
- P. Spearman
- G Calabrese (ORCID: https://orcid.org/0000-0002-0137-4595)
- Antonio Papagni (ORCID: https://orcid.org/0000-0003-2744-3883)
- Luca Vaghi (ORCID: https://orcid.org/0000-0001-5745-3826)
Institutions
- Kingston University London (GB)
- University of Milano-Bicocca (IT)
- De Montfort University (GB)
Publication Details
- Journal
- BMC Medical Imaging
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1186/s12880-024-01488-x
- Citations
- 2
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.81