Multilevel Analysis of <i>MYC</i> and <i>BCL2</i> Aberrations in Diffuse Large B‐Cell Lymphoma: Identifying a High‐Risk Patient Subgroup Across Cell‐of‐Origin Using Targeted Sequencing
We identified a distinct high-risk DLBCL subgroup, characterized by MYC and BCL2 aberrations, beyond conventional DHL-BCL2 and DEL, and irrespective of cell-of-origin, thereby expanding the poor-prognosis group.
Authors
- Michael Møller (ORCID: https://orcid.org/0000-0003-2041-3630)
- Marcus Høy Hansen (ORCID: https://orcid.org/0000-0003-3083-4850)
- Charlotte Guldborg Nyvold (ORCID: https://orcid.org/0000-0002-0411-7594)
- Thomas Stauffer Larsen (ORCID: https://orcid.org/0000-0002-8418-6708)
- Cecilie Steensboe Lang
- Tina Green (ORCID: https://orcid.org/0000-0002-4406-9291)
- Gayaththri Vimalathas (ORCID: https://orcid.org/0000-0001-5507-9762)
Institutions
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
Publication Details
- Journal
- European Journal Of Haematology
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1111/ejh.14345
- Citations
- 1
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Aarhus Universitet
- Aarhus Universitetshospital
- Kræftens Bekæmpelse
- Vissing Fonden
- Odense Universitetshospital