Different infant formulas can activate toll-like receptor 9 in vitro and inhibit interleukin 6 in human primary intestinal epithelial cells
We found out that the used control formula, prebiotic formula, prebiotic formula with hydrolyzed-protein, and L. fermentum CECT5716 reduce IL6 levels in human P-IECs through TLR9 activation. L. fermentum CECT5716 and the here tested IFs could be a promising approach for modulation of gut health in infants.
Authors
- Kathrin Hedegger
- Maik Dahlhoff (ORCID: https://orcid.org/0000-0001-9189-7631)
- Monika Schaubeck (ORCID: https://orcid.org/0000-0003-3054-7608)
- Theresa Hommel (ORCID: https://orcid.org/0000-0001-8867-0495)
- Martina Gimpfl
Institutions
- University of Veterinary Medicine Vienna (AT)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- European Journal of Nutrition
- Published
- 2024-11-21
- DOI
- https://doi.org/10.1007/s00394-024-03507-7
- Citations
- 2
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.62
Funders
- Veterinärmedizinische Universität Wien