Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking

We preliminarily revealed the potential protective effects of IAA against DOR through multiple targets and pathways, which provides a new research strategy for the molecular mechanism of IAA to alleviate DOR in the future. However, further studies need to demonstrate whether IAA can be used as a compound to prevent and treat DOR.

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Publication Details

Journal
Hereditas
Published
2024-11-21
DOI
https://doi.org/10.1186/s41065-024-00348-6
Primary Topic
Endometriosis Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking

Dandan Guan, Panpan Jing, Haofei Shen, Yanbiao Jiang et al.
Hereditas
Endometriosis Research and Treatment
article

Predicting the therapeutic role and potential mechanisms of Indole-3-acetic acid in diminished ovarian reserve based on network pharmacology and molecular docking

Dandan Guan, Panpan Jing, Haofei Shen, Yanbiao Jiang, Ahui Liu, Bin Wang, Xuehong Zhang, Jianxiu Zheng, Liulin Yu, Liyan Wang
article en

Abstract

We preliminarily revealed the potential protective effects of IAA against DOR through multiple targets and pathways, which provides a new research strategy for the molecular mechanism of IAA to alleviate DOR in the future. However, further studies need to demonstrate whether IAA can be used as a compound to prevent and treat DOR.

HereditasVol. 161(1)
First Hospital of Lanzhou University (CN), Lanzhou University (CN)
Lanzhou University
Openalex Percentile: Top 68%
Endometriosis Research and Treatment
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