Correlation of the abundance of MDSCs, Tregs, PD-1, and PD-L1 with the efficacy of chemotherapy and prognosis in gastric cancer
In advanced gastric cancer, reduced peripheral blood MDSC and Treg levels postchemotherapy and negative PD-1 and PD-L1 expression in tissues are associated with improved chemotherapy efficacy and are independent prognostic factors for PFS and OS.
Authors
- Shimin Tang (ORCID: https://orcid.org/0000-0002-9220-3707)
- Hongbo Gao (ORCID: https://orcid.org/0009-0002-2992-3960)
- Jing Li (ORCID: https://orcid.org/0000-0001-7792-4322)
- Yong Li (ORCID: https://orcid.org/0000-0001-8838-1714)
- Na Li (ORCID: https://orcid.org/0009-0001-8624-0114)
- Yun Li (ORCID: https://orcid.org/0000-0003-1915-3253)
Institutions
- Suizhou Central Hospital (CN)
- 302 Military Hospital of China (CN)
- First Affiliated Hospital of Shihezi University Medical College (CN)
Publication Details
- Journal
- Laboratory Medicine
- Published
- 2024-11-20
- DOI
- https://doi.org/10.1093/labmed/lmae090
- Citations
- 6
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.44