A new stress test for ryanodine receptors
JGP study (Steinz et al. https://doi.org/10.1085/jgp.202313515) reveals that oxidative stress can induce stable posttranslational modifications of RyR1 that increase the channel's open probability and could therefore disrupt muscle contractility.
Authors
- Ben Short (ORCID: https://orcid.org/0000-0001-7899-7881)
Institutions
- Rockefeller University Press (US)
- Rockefeller University (US)
Publication Details
- Journal
- The Journal of General Physiology
- Published
- 2024-11-12
- DOI
- https://doi.org/10.1085/jgp.202413716
- Primary Topic
- Ion channel regulation and function
- Type
- article
- Field-Weighted Citation Impact
- 0.00