[Electroacupuncture of "Jiaji" (EX-B2) inhibits inflammatory response by regulating HMGB1/TLR4/NF-κB signaling pathway in rats with spinal cord injury].

EA of "Jiaji" can promote the recovery of SCI neurological function, which may be related to its function in regulating the HMGB1/TLR4/NF-κB signaling pathway, down-regulating the expression of iNOS and COX-2, and inhibiting the neuroinflammatory response after SCI.

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Publication Details

Journal
PubMed
Published
2024-11-25
DOI
https://doi.org/10.13702/j.1000-0607.20230902
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
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article

[Electroacupuncture of "Jiaji" (EX-B2) inhibits inflammatory response by regulating HMGB1/TLR4/NF-κB signaling pathway in rats with spinal cord injury].

Xinyu Zhou, Shuang Zhong, Zhongren Sun, Yuxin Wang et al.
PubMed
Neuroinflammation and Neurodegeneration Mechanisms
article

[Electroacupuncture of "Jiaji" (EX-B2) inhibits inflammatory response by regulating HMGB1/TLR4/NF-κB signaling pathway in rats with spinal cord injury].

Xinyu Zhou, Shuang Zhong, Zhongren Sun, Yuxin Wang, Yang Cui, Jia-Min Zhu, Hong-Na Yin, J L Yang, Shuo Zhang
article en

Abstract

EA of "Jiaji" can promote the recovery of SCI neurological function, which may be related to its function in regulating the HMGB1/TLR4/NF-κB signaling pathway, down-regulating the expression of iNOS and COX-2, and inhibiting the neuroinflammatory response after SCI.

PubMedVol. 49(11)
Heilongjiang University of Chinese Medicine (CN)
Neuroinflammation and Neurodegeneration Mechanisms
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