Opioids and Dementia in the Danish Population
This study found that opioid use of less than 90 TSDs was not significantly associated with increased dementia risk. Above 90 TSDs of opioid use was associated with an elevated dementia risk before age 90 years, which persisted in individuals with chronic noncancer pain and in individuals solely exposed to weak opioids. Further research should ascertain whether the findings denote causality between opioids and dementia risk.
Authors
- Gunhild Waldemar (ORCID: https://orcid.org/0000-0003-0293-220X)
- Thomas Munk Laursen (ORCID: https://orcid.org/0000-0001-6934-1784)
- Nelsan Pourhadi (ORCID: https://orcid.org/0000-0002-5647-1018)
- Christina Jensen‐Dahm (ORCID: https://orcid.org/0000-0001-7946-6556)
- Janet Janbek (ORCID: https://orcid.org/0000-0003-1605-3396)
- Christiane Gasse (ORCID: https://orcid.org/0000-0001-6194-1099)
Institutions
- University of Copenhagen (DK)
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Copenhagen University Hospital (DK)
- Rigshospitalet (DK)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.45904
- Citations
- 6
- Primary Topic
- Pain Management and Opioid Use
- Type
- article
- Field-Weighted Citation Impact
- 3.85
Funders
- Ministeriet Sundhed Forebyggelse