Severely Hyperammonemic Acute Liver Failure due to Paracetamol Overdose: The Impact of High-Intensity Continuous Renal Replacement Therapy
Early transplant-free survival is achievable in most patients with paracetamol-induced ALF and severe hyperammonemia with a treatment based on high-intensity CRRT. Such transplant-free survival increased over time together with increased CRRT dose.
Authors
- Rinaldo Bellomo (ORCID: https://orcid.org/0000-0002-1650-8939)
- Sofia Spano (ORCID: https://orcid.org/0000-0001-8556-4937)
- Stephen Warrillow (ORCID: https://orcid.org/0000-0002-7240-4106)
- Caleb Fisher (ORCID: https://orcid.org/0000-0003-3336-3898)
- Yukiko Hikasa (ORCID: https://orcid.org/0000-0001-6133-765X)
- Glenn M. Eastwood (ORCID: https://orcid.org/0000-0001-7700-9933)
- Akinori Maeda (ORCID: https://orcid.org/0009-0004-7388-9450)
- Scott Warming (ORCID: https://orcid.org/0000-0001-9113-8598)
- Anis Chaba (ORCID: https://orcid.org/0000-0003-2694-7051)
- Nuanprae Kitisin (ORCID: https://orcid.org/0000-0001-9703-3551)
- Atthaphong Phongphithakchai (ORCID: https://orcid.org/0000-0001-8422-2644)
- Nuttapol Pattamin (ORCID: https://orcid.org/0009-0008-5125-9756)
- Claire Michel
Institutions
- The University of Melbourne (AU)
- Austin Hospital (AU)
- Australian and New Zealand Intensive Care Society (AU)
- Peninsula Health (AU)
- Monash University (AU)
Publication Details
- Journal
- Blood Purification
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1159/000542556
- Citations
- 4
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 1.87