Combination Therapy with Secretome of Reovirus-Infected Mesenchymal Stem Cells and Metformin Improves Anticancer Effects of Irinotecan on Colorectal Cancer Cells in vitro
We highlight that the combination of ReoT3D-derived secretome with irinotecan and metformin showed a synergistic anticancer effect on the CT26 cell line, and this strategy may be considered as a new approach against colorectal cancer in the in vitro and in vivo in future studies.
Authors
- Maliheh Elhamipour
- Hoorieh Soleimanjahi (ORCID: https://orcid.org/0000-0003-1931-7801)
- Asghar Abdoli
- Hesam Karimi (ORCID: https://orcid.org/0000-0002-6262-4551)
- Negar Sharifi
- Ruth Kvistad
- Saeed Soleyman jahi
Institutions
- Pasteur Institute of Iran (IR)
- Tarbiat Modares University (IR)
- Washington University in St. Louis (US)
- University of Missouri–St. Louis (US)
Publication Details
- Journal
- Intervirology
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1159/000542356
- Citations
- 7
- Primary Topic
- Virus-based gene therapy research
- Type
- article
- Field-Weighted Citation Impact
- 3.85
Funders
- Tarbiat Modares University
- Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu