POU3F4 up-regulates Gli1 expression and promotes neuronal differentiation and synaptic development of hippocampal neural stem cells
The results suggest that POU3F4 and Gli1 promote neuronal differentiation and synaptic development of NSCs, and that Gli1 partially mediates the effects of POU3F4.
Authors
- Xunrui Zhang
- Naijuan Xu
- Yaya Ji (ORCID: https://orcid.org/0000-0003-4084-1165)
- Meiling Tian
- Yujian Lin (ORCID: https://orcid.org/0000-0002-0500-4217)
- Xinhua Zhang (ORCID: https://orcid.org/0000-0002-5702-6733)
- Wen Li (ORCID: https://orcid.org/0000-0002-6807-479X)
- Lei Zhang (ORCID: https://orcid.org/0009-0008-9783-092X)
- Cheng Xiang (ORCID: https://orcid.org/0000-0002-1229-6860)
- Min Xu (ORCID: https://orcid.org/0009-0003-5839-0259)
- Haoming Li (ORCID: https://orcid.org/0000-0002-4664-2055)
- Xiao Han (ORCID: https://orcid.org/0000-0001-6527-4502)
- Jingjing Guo (ORCID: https://orcid.org/0000-0002-2411-0082)
- Jianbing Qin (ORCID: https://orcid.org/0000-0003-0001-750X)
- Ruijie Ji
- Jue Wang (ORCID: https://orcid.org/0000-0001-8149-1566)
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Yancheng Third People's Hospital (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1186/s13287-024-04043-1
- Citations
- 2
- Primary Topic
- Neurogenesis and neuroplasticity mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.82
Funders
- National Natural Science Foundation of China