Associations between maternal <i>MTHFR</i> polymorphisms and embryological outcomes in Korean patients with infertility undergoing IVF/ICSI cycles
<i>MTHFR</i> 677TT genotype, which had the lowest enzymatic activity, had the lowest oocyte maturation rate. The combined <i>MTHFR</i> 677CC/1298CC, 677CT/1298AA, and 677CT/1298AC genotypes with intermediate enzyme activities had higher GQE rates. However, no differences were observed in the transplantable embryo rate between <i>MTHFR</i> genotypes.
Authors
- Tae Hyong Kim (ORCID: https://orcid.org/0000-0003-2920-9038)
- Yoo Ra Ko (ORCID: https://orcid.org/0000-0002-0738-4153)
- Woo Sik Lee (ORCID: https://orcid.org/0000-0002-2329-1774)
- Eum Jin Hee
- Se Jeong Kim (ORCID: https://orcid.org/0000-0003-1879-3451)
Institutions
- CHA University (KR)
- CHA University Gangnam Medical Center (KR)
Publication Details
- Journal
- Gynecological Endocrinology
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1080/09513590.2024.2431224
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00