Associations of epigenetic age acceleration at birth and age 12 years with adolescent cardiometabolic risk: the HOME study
Our findings provide evidence that faster pace of biological aging was associated with higher cardiometabolic risk score, visceral fat, and HbA1c at age 12 years. Further research is needed to determine whether these associations persist from adolescence through adulthood.
Authors
- Kim M. Cecil (ORCID: https://orcid.org/0000-0001-8233-5485)
- Karl T. Kelsey (ORCID: https://orcid.org/0000-0002-2302-1600)
- Kimberly Yolton (ORCID: https://orcid.org/0000-0002-4458-0516)
- Scott M. Langevin (ORCID: https://orcid.org/0000-0001-7031-1216)
- Jessie Poulin Buckley (ORCID: https://orcid.org/0000-0001-7976-0157)
- George D. Papandonatos (ORCID: https://orcid.org/0000-0001-6770-932X)
- Bruce P. Lanphear (ORCID: https://orcid.org/0000-0003-2598-5574)
- Jennifer Arzu (ORCID: https://orcid.org/0000-0003-3990-3146)
- Aimin Chen (ORCID: https://orcid.org/0000-0001-9713-6438)
- Joseph M. Braun (ORCID: https://orcid.org/0000-0002-5239-3235)
Institutions
- University of Vermont (US)
- University of North Carolina at Chapel Hill (US)
- Cincinnati Children's Hospital Medical Center (US)
- Simon Fraser University (CA)
- Brown University (US)
- University of Cincinnati (US)
- University of Pennsylvania (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1186/s13148-024-01779-8
- Citations
- 4
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 4.44
Funders
- National Institutes of Health