A multicentre prospective registry of one thousand sepsis patients admitted in Indian ICUs: (SEPSIS INDIA) study
The general demographics of the sepsis population in the Indian Sepsis Registry is comparable to Western population. The mortality of sepsis cohort was higher (36.3%) but septic shock mortality (50.8%) was comparable to Western reports. Gram negative infection was the predominant cause of sepsis with a high incidence of carbapenem resistance. Eschericia coli, Klebsiella Spp and Acinetobacter Spp were the predominant causative organism. Tropical infection constituted a minority of sepsis population with low hospital mortality. The SOFA score on admission was a comparatively better predictor of poor outcome. Sepsis secondary to nosocomial infections had the worst outcomes, while source control, correct empirical antibiotic selection, and intravenous thiamine were protective. CTRI Registration CTRI:2022/07/044516.
Authors
- Deepak Govil (ORCID: https://orcid.org/0000-0002-4624-1614)
- Subhash Kumar Todi (ORCID: https://orcid.org/0000-0003-2306-6080)
- Gaurav Kochhar
- Abhijit Deshmukh (ORCID: https://orcid.org/0000-0001-5602-291X)
- Swarna Deepak Kuragayala
- Palepu Gopal (ORCID: https://orcid.org/0000-0002-5261-1730)
- Sumalatha Arunachala
- Chitra Mehta (ORCID: https://orcid.org/0000-0002-6738-1042)
- Srinivas Samavedam (ORCID: https://orcid.org/0000-0001-6737-8663)
- Pranita Ashok
- Amit Saha (ORCID: https://orcid.org/0000-0002-3542-4319)
- Saanvi Ambapkar (ORCID: https://orcid.org/0000-0003-2758-9073)
- Sweta Patel (ORCID: https://orcid.org/0000-0002-4052-7160)
- Rahul Pandit
- Kapil Borawake (ORCID: https://orcid.org/0000-0003-4527-3734)
- Kapil Gangadhar Zirpe (ORCID: https://orcid.org/0000-0002-8140-727X)
- Ajoy Krishna Sarkar
- Anjana Srivastav
- Shilpushp J Bhosale (ORCID: https://orcid.org/0000-0002-0290-0526)
- Mehul Shah (ORCID: https://orcid.org/0000-0003-2811-3915)
- Sushmita Basu (ORCID: https://orcid.org/0000-0002-9182-1191)
- Deepa L. Sekhar (ORCID: https://orcid.org/0000-0002-5784-7216)
- Amitabha Saha
- Ruta Shanmugam (ORCID: https://orcid.org/0009-0000-4376-4316)
- Anand M Tiwari (ORCID: https://orcid.org/0000-0002-9791-8365)
- Sourabh Ambapkar (ORCID: https://orcid.org/0000-0002-0636-3879)
- Sushma Gurav (ORCID: https://orcid.org/0000-0001-6875-2071)
- Ruchi Gupta (ORCID: https://orcid.org/0000-0003-2419-165X)
- Shweta Ram Chandankhede (ORCID: https://orcid.org/0000-0002-6684-1406)
- Abdul Samad Ansari
- Atul P Kulkarni (ORCID: https://orcid.org/0000-0002-5172-7619)
- Yatin Mehta
- Sumit Ray (ORCID: https://orcid.org/0000-0001-5192-4711)
- Subhal Dixit (ORCID: https://orcid.org/0009-0007-2873-6916)
- Ashit Hegde (ORCID: https://orcid.org/0000-0003-4342-122X)
- K. B. Chetak
- muhammad umair abdul qadir
- Mayur Shah
- Fahima Begum
- P. Kaushik
- Anita Salgar
- Rahul Hurne
Institutions
- Apollo Hospitals (IN)
- Holy Family Hospital (IN)
- Gandhi Medical College & Hospital (IN)
- Homi Bhabha National Institute (IN)
- Sir H.N. Reliance Foundation Hospital and Research Centre (IN)
- Tata Memorial Hospital (IN)
- P. D. Hinduja Hospital and Medical Research Centre (IN)
- Ruby Hall Clinic (IN)
- Max Super Speciality Hospital (IN)
- CARE Hospitals (IN)
- Lourdes Hospital (IN)
- National Hospital (IN)
- Hindu Rao Hospital (IN)
- Medanta The Medicity (IN)
- Peerless Hospital & B.K.Roy Research Centre (IN)
- Apollo Hospitals (IN)
- Sahyadri Hospital (IN)
- Manipal Hospital (IN)
- Citizens Specialty Hospitals
- Institute of Medical Sciences (IN)
- JSS Medical College and Hospital (IN)
Publication Details
- Journal
- Critical Care
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1186/s13054-024-05176-8
- Citations
- 11
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.25
Funders
- Pfizer