In vitro comparative quality evaluation of different brands of Amlodipine Tablets Commercially available in Jimma Town, South-western Ethiopia

The study revealed a manifest discrepancy in the dissolution profiles' releases. Therefore, it is strongly advised to use appropriately designed dissolution profile evaluation methods with various pH values in the dissolution media, as well as to do comprehensive visual inspections. This will make it easier to do a thorough investigation of any potential quality issues that might be related to various generic products available in the pharmaceutical market.

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Publication Details

Journal
PLoS ONE
Published
2024-11-19
DOI
https://doi.org/10.1371/journal.pone.0310828
Citations
1
Primary Topic
Pharmaceutical Quality and Counterfeiting
Type
article
Field-Weighted Citation Impact
0.54
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article

In vitro comparative quality evaluation of different brands of Amlodipine Tablets Commercially available in Jimma Town, South-western Ethiopia

Sultan Suleman, Tesfaye Mohammed, Gemmechu Hasen, Belachew Umeta et al.
1 citations
PLoS ONE
Pharmaceutical Quality and Counterfeiting
0.54
article

In vitro comparative quality evaluation of different brands of Amlodipine Tablets Commercially available in Jimma Town, South-western Ethiopia

Sultan Suleman, Tesfaye Mohammed, Gemmechu Hasen, Belachew Umeta, Yesuneh Tefera Mekasha, Abera Milkesa, Duresa Dedefo
article en
1 citations

Abstract

The study revealed a manifest discrepancy in the dissolution profiles' releases. Therefore, it is strongly advised to use appropriately designed dissolution profile evaluation methods with various pH values in the dissolution media, as well as to do comprehensive visual inspections. This will make it easier to do a thorough investigation of any potential quality issues that might be related to various generic products available in the pharmaceutical market.

PLoS ONEVol. 19(11)
Jimma University (ET), Southern Nations, Nationalities, and Peoples' Region (ET), University of Gondar (ET)
Openalex Percentile: Top 27%
Pharmaceutical Quality and Counterfeiting
0.54
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