Genetic association of tertiary lymphoid structure-related gene signatures with HCC based on Mendelian randomization and machine learning and construction of prognosis model
3 TLSGs identified by machine learning and MR can predict the onset, prognosis and clinical treatment of HCC patients, and had significant genetic association with HCC.
Authors
- LI Jian-yue
- Chuanying Xi (ORCID: https://orcid.org/0000-0003-3179-7019)
- Pu Cheng (ORCID: https://orcid.org/0000-0001-6358-5219)
- Xiaorong Wang (ORCID: https://orcid.org/0000-0002-1912-3890)
- Chunyuan Zhang (ORCID: https://orcid.org/0000-0002-0944-2708)
- Xiaoyan Zhang (ORCID: https://orcid.org/0000-0002-9664-1560)
- Jiacheng Zhou (ORCID: https://orcid.org/0009-0004-6192-9988)
- Pu Lei (ORCID: https://orcid.org/0009-0001-8240-4011)
Institutions
- Shanghai University of Sport (CN)
- Integrated Chinese Medicine (China) (HK)
- Shanxi Province Hospital of Traditional Chinese Medicine (CN)
- Taixing People's Hospital (CN)
- Shandong First Medical University (CN)
- Anyang Hospital of Traditional Chinese Medicine (CN)
- East China Normal University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1016/j.intimp.2024.113594
- Citations
- 5
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.43