The prognostic role of ACSL4 in postoperative adjuvant TACE-treated HCC: implications for therapeutic response and mechanistic insights
The CEBPA-ACSL4 pathway is critical in protecting HCC cells from glucose starvation-induced cell death, suggesting that ACSL4 and CEBPA could serve as valuable prognostic indicators and potential therapeutic targets in the context of PA-TACE treatment for HCC.
Authors
- Shing Chuan Hooi (ORCID: https://orcid.org/0000-0003-3249-903X)
- Guo‐Huan Yang (ORCID: https://orcid.org/0009-0008-3287-4454)
- Jing Zhou (ORCID: https://orcid.org/0000-0002-2475-7783)
- Xiwen Liao (ORCID: https://orcid.org/0000-0002-1724-1463)
- Guangzhi Zhu (ORCID: https://orcid.org/0000-0001-5958-7289)
- Tao Peng (ORCID: https://orcid.org/0000-0001-6133-7078)
- Peizhi Lu
- Yock Young Dan (ORCID: https://orcid.org/0000-0002-7546-2117)
- Guo‐Dong Lu (ORCID: https://orcid.org/0000-0001-6056-3196)
- Yue Tang (ORCID: https://orcid.org/0000-0002-2519-4505)
- Yong Wu (ORCID: https://orcid.org/0000-0002-1698-0897)
- Jin-Lian Bin
- Qian-Ru Cui
- Jing-Huan Deng (ORCID: https://orcid.org/0000-0002-2899-8701)
- Lixin Li (ORCID: https://orcid.org/0000-0003-3016-4228)
- Feng Ji
Institutions
- Sun Yat-sen University (CN)
- Guangxi Medical University (CN)
- National University of Singapore (SG)
- Fudan University (CN)
- Shanghai Public Health Clinical Center (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Tumor Hospital of Guangxi Medical University (CN)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1186/s13046-024-03222-5
- Citations
- 8
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.28
Funders
- National Natural Science Foundation of China
- Servier
- Education Department of Guangxi Zhuang Autonomous Region
- Guangxi Medical University