Association of Pulmonary Hypertension With Trastuzumab Emtansine
Our results suggest that more patients exposed to trastuzumab emtansine developed PH compared with trastuzumab alone. Further assessment of this safety signal and exploration of pathophysiologic mechanisms is needed.
Authors
- Vincent Cottin (ORCID: https://orcid.org/0000-0002-5591-0955)
- Charles Khouri (ORCID: https://orcid.org/0000-0002-8427-8573)
- Étienne-Marie Jutant (ORCID: https://orcid.org/0000-0002-1374-1890)
- S. Palat (ORCID: https://orcid.org/0000-0003-2292-6253)
- Julien Grynblat (ORCID: https://orcid.org/0000-0001-5593-3383)
- Guillaume Beltramo (ORCID: https://orcid.org/0000-0003-2830-5642)
- Marie‐Camille Chaumais (ORCID: https://orcid.org/0000-0002-1217-8442)
- Camille Poisson (ORCID: https://orcid.org/0009-0005-5853-2127)
- Benoît Lechartier (ORCID: https://orcid.org/0000-0001-5932-8164)
- Fabrice Antigny (ORCID: https://orcid.org/0000-0002-9515-6571)
- Arnaud Maurac (ORCID: https://orcid.org/0000-0003-0390-266X)
- Alex Hlavaty (ORCID: https://orcid.org/0009-0002-8483-5023)
- Nicolas Favrolt (ORCID: https://orcid.org/0000-0002-3497-3308)
- Philippe Bonniaud (ORCID: https://orcid.org/0000-0002-3670-5622)
- David Montani (ORCID: https://orcid.org/0000-0002-9358-6922)
- Marc Humbert (ORCID: https://orcid.org/0000-0003-0703-2892)
- Pierre Mouillot
- Laurie Rambach
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Inserm (FR)
- Université Paris-Saclay (FR)
- Centre Hospitalier Universitaire de Grenoble (FR)
- Centre Hospitalier Universitaire Vaudois (CH)
- Université de Poitiers (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospices Civils de Lyon (FR)
- Centre Chirurgical Marie Lannelongue (FR)
- Hypertension pulmonaire : physiopathologie et innovation thérapeutique (FR)
- CHU Dijon Bourgogne (FR)
- Hôpital Marie Lannelongue (FR)
- Hôpital Cardiologique du Haut-Lévêque (FR)
- Hôpital Louis Pradel (FR)
- Centre Hospitalier Public du Cotentin (FR)
- Bicêtre Hospital (FR)
- Université de Limoges (FR)
- Université Grenoble Alpes (FR)
Publication Details
- Journal
- CHEST Journal
- Published
- 2024-11-19
- DOI
- https://doi.org/10.1016/j.chest.2024.11.006
- Citations
- 6
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.51
Funders
- United Therapeutics Corporation
- Acceleron