Dehydrated amniotic membrane patch for the treatment of an ocular event secondary to mirvetuximab soravtansine-gynx (MIRV) therapy

•Mirvetuximab soravtansine (MIRV) is used in the treatment of FRα positive, platinum-resistant epithelial ovarian cancer.•MIRV is associated with ocular events, leading to dose delays, dose reductions, and discontinuations of chemotherapy.•Mitigation strategies to prevent treatment disruption have historically relied on corticosteroid and lubricating drops.•Dehydrated amniotic membrane patch to treat MIRV related ocular events is a novel therapeutic option.

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Publication Details

Journal
Gynecologic Oncology Reports
Published
2024-11-19
DOI
https://doi.org/10.1016/j.gore.2024.101547
Citations
1
Primary Topic
Corneal Surgery and Treatments
Type
article
Field-Weighted Citation Impact
0.40
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article

Dehydrated amniotic membrane patch for the treatment of an ocular event secondary to mirvetuximab soravtansine-gynx (MIRV) therapy

Brittany File, Anjali Hari, Ling Bei
1 citations
Gynecologic Oncology Reports
Corneal Surgery and Treatments
0.40
article

Dehydrated amniotic membrane patch for the treatment of an ocular event secondary to mirvetuximab soravtansine-gynx (MIRV) therapy

Brittany File, Anjali Hari, Ling Bei
article en
1 citations

Abstract

•Mirvetuximab soravtansine (MIRV) is used in the treatment of FRα positive, platinum-resistant epithelial ovarian cancer.•MIRV is associated with ocular events, leading to dose delays, dose reductions, and discontinuations of chemotherapy.•Mitigation strategies to prevent treatment disruption have historically relied on corticosteroid and lubricating drops.•Dehydrated amniotic membrane patch to treat MIRV related ocular events is a novel therapeutic option.

Gynecologic Oncology ReportsVol. 56
MemorialCare Long Beach Medical Center (US), University of California, Irvine Medical Center (US)
Openalex Percentile: Top 33%
Corneal Surgery and Treatments
0.40
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